Significant improvement in MoCA scores after antiretroviral therapy (ART) indicates that ART positively affected cognitive functions.The most impacted cognitive functions were delayed recall and attention in HIV-infected patients.MoCA test is recommended as an alternative for screening and follow-up purposes in HIV-infected patients because it is sensitive to mild cognitive impairment and can monitor the cognitive functions frequently affected by HIV.Keywords: antiretroviral treatment, cognitive functions, HIV, MoCA test, neurocognitive disorders Highlights There was a significant increase in the total MoCA score and the MoCA subgroup scores at the end of the sixth month of the treatment.Ĭonclusion: MoCA test is one of the most practical tests that can be applied in a short time period, and it was found useful in evaluating the changes in the cognitive functions of HIV-positive patients during antiretroviral treatment. A significant correlation was found between cluster differentiation 4 (CD4) count and HIV RNA level and attention function. Smoking, using alcohol, and substance did not have a significant impact on baseline MoCA values. When the factors affecting the MoCA score were examined, there was a significant relationship between the education level and the MoCA score. Results: Forty male patients were included in the study. The MoCA test was performed at the beginning and the sixth month of the treatment. Materials and Methods: HIV-positive, treatment-naïve patients monitored between January-June 2017 were included in the study. This study aimed to evaluate cognitive functions and the factors affecting them in naïve HIV-positive patients using by Montreal Cognitive Assessment (MoCA) test before and after the initiation of combination antiretroviral therapy. Objective: In the determination and monitoring of neurocognitive disorders in human immunodeficiency virus (HIV)-positive individuals, there is a need for significantly more practical methods which provide results in a shorter time than the tests that require challenging and specialized expertise. This work is licensed under a Creative Commons Attribution-Non Commercial 4.0 International License. Cognitive assessment of young adults before and after initiation of combination antiretroviral therapy. Gül Ö, Gündüz A, Sevgi DY, Demirbaş ND, Uzun N, Dökmetaş İ.
0 kommentar(er)
